A Case of Isolated Aspergillus Sphenoid Sinusitis

J Korean Neurol Assoc > Volume 23(3); 2005 > Article

Journal of the Korean Neurological Association 2005;23(3): 402-404.

단독성 아스페르길루스 접형동염 1예

김대현, 김효경 남정권a 박지강b

울산대학교 의과대학 울산대학교병원 신경과, 이비인후과a, 진단방사선과b

A Case of Isolated Aspergillus Sphenoid Sinusitis

Dae-Hyun Kim

Departments of Neurology, Otolaryngologya, and Radiologyb, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea

Abstract

Isolated Aspergillus infection originating within the sphenoid sinus is most often associated with the immunocompromised patient. A 53-year-old healthy woman presented with a 3-week history of headache and subsequent left 6th nerve palsy. Brain MRI demonstrated a space-occupying lesion within sphenoid sinus. Histological analysis through transnasal-transsphenoidal approach revealed numerous Aspergillus hyphae. Postoperatively, all symptoms resolved completely without anti-fungal treatment. Isolated Aspergillus sphenoid sinusitis should be routinely included in the differential diagnosis of patients with acute or subacute headache, even in nonimmunosuppressed patients.KeyWords:Aspergillosis, Sphenoid sinus, Isolated sphenoiditis