Multiphasic Disseminated Encephalomyelitis (MDEM); 
Report of 3 Cases

J Korean Neurol Assoc > Volume 23(3); 2005 > Article

Journal of the Korean Neurological Association 2005;23(3): 392-395.

다상성파종성뇌척수염 3예

서범천, 김승민 김흥동a 신하영 조정희 선우일남

연세대학교 의과대학 신경과학교실, 소아과학교실

Multiphasic Disseminated Encephalomyelitis (MDEM); Report of 3 Cases

Bum Chun Suh

Departments of Neurology and Pediatricsa, Yonsei University College of Medicine, Seoul, Korea

Abstract

We report 3 cases of recurrent acute disseminated encephalomyelitis (ADEM) known as multiphasic disseminated encephalomyelitis (MDEM). The 3 cases presented with fever, headache, neck stiffness, abdominal pain, seizure and decreased mentality as well as focal neurologic deficits, which showed relatively good steroid responsiveness. Brain MRI revealed variable sized, multifocal, subcortical white matter lesions with gray matter involvement. The CSF study showed mild pleocytosis with negative oligoclonal band. KeyWords:Acute disseminated encephalomyelitis, Multiphasic disseminated encephalomyelitis