A Case of Polymyositis associated with Hepatitis B infection

J Korean Neurol Assoc > Volume 20(3); 2002 > Article

Journal of the Korean Neurological Association 2002;20(3): 315-317.

B형 간염과 연관된 다발성근염 1예

신상건 , 조인수 한병인 홍지만 주성렬

아주대학교 의과대학 신경과학교실, 병리학교실

A Case of Polymyositis associated with Hepatitis B infection

Sang-Kun Sin, M.D.

Department of Neurology, Department of Pathology, College of Medicine, Ajou University

Abstract

"Polymyositis(PM) is one of idiopathic inflammatory myopathy, characterized by proximal muscle weakness, myalgia and muscle enzyme elevation. Currently the main pathogenesis is well documented, the cell-mediated immunity. We experienced a case of polymyositis associated with hepatitis, developed after hepatitis B virus(HBV) infection. This virus-induced autoimmunity seems to result from the cross-reactivity between muscle protein and B-viral antigen, so called antigenic mimicry. This relation of PM and HBV is more significant in Korea because of the epidemicity of HBV infection.Key Words : Polymyositis, Hepatitis, Hepatitis B virus"