J Korean Neurol Assoc > Volume 20(1); 2002 > Article

Journal of the Korean Neurological Association 2002;20(1): 89-92.

"Anti-Hu 항체 양성의 부수종양성 아급성 감각신경원병증 1례"

신진홍, 조한진 김대성 정대수 박규현 이민기 박순규

부산대학교 의과대학 신경과학교실, 내과학교실

"A Case of Anti-Hu Associated Paraneoplastic Subacute Sensory Neuronopathy"

Jin-Hong Shin

Department of Neurology and Department of Internal Medicine*, College of Medicine, Pusan National University

Abstract

"Subacute sensory neuronopathy usually occurs as a paraneoplastic syndrome, occurring most frequently in small cell lung cancer. We report a 63-year-old male presenting typical symptoms of subacute sensory neuronopathy. Electrophysiologic studies showed diffuse sensory axonal degeneration and anti-Hu antibody was positive in his serum. We reevaluated pulmonary lesions formerly diagnosed as active pulmonary tuberculosis. Chest computed tomography showed two nodules and hilar lymphadenopathy, and by percutaneous needle biopsy, small cell lung cancer was diagnosed.Key Words : Paraneoplastic sensory neuronopathy, Small cell lung cancer, Anti-Hu antibody"