J Korean Neurol Assoc > Volume 19(5); 2001 > Article

Journal of the Korean Neurological Association 2001;19(5): 498-502.

말초성 전정장애에서 전정유발 근원성전위 검사의 유용성

김현영, 박기형 ·김승현 ·김희태 ·김주한 ·김명호 ·성기범*

한양대학교 의과대학 신경과학교실,순천향대학교 의과대학 신경과학교실*

"Significance of Vestibular Evoked Myogenic Potentials in Peripheral Vestibulopathy"

"Hyun-Young Kim M.D., Kee-Hyung Park M.D., Hee-Tae Kim M.D., Seung-Hyun Kim M.D., Juhan Kim M.D., Myung-Ho Kim M.D., Ki-Bum Sung M.D.*"

"Department of Neurology, College of Medicine, Hanyang University, Department of Neurology, College of Medicine, Soonchunhyang University*"

Abstract

"Background : Loud monaural clicks evoke myogenic potentials in the tonically contracting ipsilateral sternocleido-mastoid muscle. Clinical studies have suggested that these myogenic potentials are of vestibular origin, especially infe-rior vestibular nerve. Neurophysiological experimental studies also suggest that they are most likely to be of saccular origin. These potentials are called vestibular evoked myogenic potentials (VEMPs). Vestibular neuritis (VN) affects only part of the vestibular nerve trunk, usually the superior division (horizontal canal paresis) which may be detected by caloric test. But inferior vestibular nerve involvement in VN may not be detected by caloric test. So we compared the results of caloric test and VEMPs in patients with VN, in order to evaluate inferior vestibular nerve function. Methods : Twenty-one normal controls were selected to determine the normal data of VEMPs. Patients group was consisted of clinically suspected peripheral vertigo [vestibular neuritis 10, benign paroxysmal positional vertigo of the posterior semicircular canal (PSC-BPPV) 7, Meniere’s disease 3]. Caloric test and VEMPs were performed in all subjects accord-ing to our protocol. Results : Normal VEMPs responses were found in all control groups. In all VN patients, caloric test was unilaterally abnormal and abnormal VEMPs was found in 4 of 10 VN patients. In patients with PSC-BPPV, abnor-mal caloric response was found in 2 of 7 patients but p13/n23 in VEMPs was present normally in all patients. Conclusions : These results suggest that VEMPs could provide different information from the caloric test and could be helpful in evaluating inferior vestibular nerve involvement in patients with peripheral vestibulopathy. J Korean Neurol Assoc 19(5):498~502, 2001 Key Words : Vestibular evoked myogenic potential, Caloric test, Peripheral vestibulopathy"