The Relationship between Febrile Convulsion and Temporal Lobe Epilepsy :
Is Febrile Convulsion a Preferential Association with Temporal Lobe Epilepsy ?

J Korean Neurol Assoc > Volume 18(4); 2000 > Article

Journal of the Korean Neurological Association 2000;18(4): 409-413.

열성 경련과 측두엽 간질의 관계 : 열성 경련을 경험한 성인 간질 환자에서 측두엽 간질이 호발하는가?

정정욱, ·김성은 ·이태윤*·허허경 †

인제대학교 의과대학 부산백병원 신경과,동래 봉생병원 신경과*,포천중문의과대학 분당 차병원 신경과 †

The Relationship between Febrile Convulsion and Temporal Lobe Epilepsy : Is Febrile Convulsion a Preferential Association with Temporal Lobe Epilepsy ?

Jung-wook Jung, M.D., Sung-Eun Kim, M.D., Tae-Yoon Lee, M.D.*, Kyoung Heo, M.D.

Department of Neurology, Inje University Pusan Paik Hospital, Department of Neurology, Dong Rae Bong Sang Memorial Hospital* Departmemt of Neurology, Pocheon CHA University College of Medicine, Pundang CHA General Hospital

Abstract

B a c k g r o u n d : Although a history of febrile convulsion (FC) is common in epilepsy patients, the preferential associa-tion of febrile convulsion with temporal lobe epilepsy (TLE) is not clear. M e t h o d s : We obtained the FC data from “Paik and Bongsang hospital “ epilepsy clinic. We classified epilepsy syndromes into generalized epilepsy (GE), temporal lobe epilepsy (TLE), extratemporal epilepsy (ETLE), unclassified partial and undetermined epilepsy by standardized criteria. The incidence of antecedent FC was evaluated in relation to the epilepsy classifications. We calculated kappa values for inter and intra observer reliability for the classifications of epilepsy syndromes. R e s u l t s : The agreement of epilepsy classifications were reliable (intra-observer kappa value=0.78, inter-observer kappa value=0.77). Thirteen percent of the studied patients (72/537) had a history of FC and 38% of FC (27/72) were complex types of FC. TLE was more likely to be preceded by FC 25% (42/166) than ETLE 6% (12/189), p<0.05 or GE 13% (12/93), p<0.05 and 85% of complex FC (23/27) preceded TLE. GE however, was more likely to have non-complex FC 100% (12/12) than partial epilepsy 55% (32/58), p<0.05. C o n c l u s I o n s : We therefore conclude and agree that FC should be preferentially associated with TLE. J Korean Neurol Assoc 18(4):409~413, 2000 Key Words : Febrile convulsion, Temporal lobe epilepsy, Complex febrile convulsion