| 간질환자의 삶의 질에 영향을 미치는 임상적 요인 |
| 윤수영, 정승철이강연욱이이향운이이지영이서대원이홍승봉 |
| 성균관대학교 의과대학 삼성서울병원 신경과,뇌신경센터* |
| Clinical Factors Influencing Quality of Life in Patients with Epilepsy |
| Soo Young Youn, R.N.*, Seung Cheol Jeong, M.D., Yeon Wook Kang, Ph.D., Hyang Woon Lee, M.D., Jiyeong Yi, M.D., Dae Won Seo, M.D., Seung Bong Hong, M.D. |
| Department of Neurology, Neuroscience Center*, Samsung Medical Center,
Sungkyunkwan University School of Medicine |
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| Abstract |
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Background : Epilepsy has been known to adversely affect a patient’s quality of life (QOL). We investigated the sta-tus of QOL and tested the influences of clinical factors upon QOL in epileptic patients. Methods : We evaluated 125 adult patients (mean age, 30.4 years, male:female=1:0.86) with epilepsy. The demographic, social (marriage, employ-ment, religion, education duration), and clinical data (seizure onset age, seizure pattern during the last 1 year, treatment duration, number of antiepileptic drug) were obtained. Quality of life in epilepsy-31 (QOLIE-31) and Beck Depression
Inventory-Korean version (KBDI) were used. The relationships of demographic, social, and clinical factors with QOL in epileptic patients were evaluated. Results : The mean subscores of QOLIE-31 items were 52.6 (medication effects), 50.9 (cognitive functioning), 50.9 (social functioning), 50.5 (energy/fatigue), 48.4 (seizure worry), 46.8 (overall QOL), and 45.7 (emotional well-being), and the overall score was 49.6. Sex, marriage, religion, and duration of treatment did not affect QOL. The age of patients had a weak linear positive correlation with overall QOL and emotional well-being. Employed patients had a significantly high score in overall QOL, emotional well-being, cognitive functioning, social functioning, and overall score. The patients given polytherapy had lower scores of QOLIE-31 items except seizure worry and energy/fatigue. Seizure free patients had significantly higher scores in seizure worry, overall QOL, social functioning, and overall score. Depression negatively influenced all subscales and overall score. Conclusions : Age, employment state, number of antiepileptic drugs, seizure pattern, and depression were significant clinical factors affect -ing QOL in patients with epilepsy.
J Korean Neurol Assoc 18(2):156~161, 2000 Key Words : Quality of life, Epilepsy, QOLIE-31, Beck Depression Inventory Manuscript received September 14,1999. Accepted in final form December 24,1999. *Address for correspondence Seung Bong Hong, M.D. |
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