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Journal of the Korean Neurological Association 1999;17(5): 764-766.
Marchiafava-Bignami disease 2예
오병철, 양윤정 ·김영현*
전북대학교 의과대학 신경과학교실,의과학 연구소*
Two Cases of Marchiafava-Bignami Disease
Byeong Cheol Oh, M.D., Yun Jeong Yang, M.D., Young Hyun Kim, M.D.*
Department of Neurology, Chonbuk National University Medical School and Institute for Medical Sciences*
We described 2 patients with Marchiafava-Bignami disease, a neurological disorder associated with chronic alcohol consumption. Patient 1 expressed general weakness and confusion, while patient 2 expressed dysphagia and seizures. Lesions involving the corpus callosum were identified with T2 weighted MR imaging in which there was a hyperinten-sity in the splenium of patient 1 and in the entire corpus callosum of patient 2. While the conditions of both patients were improved by with nutritional support, they were left with cognitive impairment. J Kor Neurol Ass 17(5):764~766, 1999 Key Words : Marchiafava-Bignami disease, Corpus callosum, Demyelination