Clinical Characteristics of Ischemic Stroke after Octogenarian Age : A Hospital-based Study

J Korean Neurol Assoc > Volume 17(5); 1999 > Article

Journal of the Korean Neurological Association 1999;17(5): 609-614.

80세 이상의 허혈성 뇌졸중 환자의 임상적 특성 : 병원 중심 연구

오윤민, 김장성

아주대학교 의과대학 신경과학교실

Clinical Characteristics of Ischemic Stroke after Octogenarian Age : A Hospital-based Study

Youn-Min Oh, M.D., Jang-Sung Kim, M.D.

Department of Neurology, Ajou University Hospital

Abstract

Background : Although the incidence of stroke does not decrease after 80 years of age. The significance of ischemic stroke (IS) after octogenarian age has not attracted the attention of neurologists. As a first step to investigate the signifi-cance of IS during that period, we compared the clinical characteristics of IS between OIS (octogenarian ischemic stroke group, ??80 years of age) and NOIS (non-octogenarian ischemic stroke group, 65-79 years of age). Methods : Forty-nine OIS patients and 141 NOIS patients were recruited. Clinical characteristics including risk factors, IS sub-type, Canadian Neurological Scale (CNS) score, treatment modality and short-term prognosis were evaluated and described. Results : ypertension (65.3%) was the most common risk factor followed by smoking (28.6%) and previ-ous stroke history (28.6%) in OIS. There was no significant difference in proportion of each IS risk factors between he two groups. OIS was more associated with subtypes of mixed etiology and cardiogenic embolism than NOIS (P<.05). Subclassification by the vascular territory of IS was similar between the two groups and the middle cerebral arterial ter-ritory was the most common site (71.1%) in OIS. CNS scores on the initial neurological examination was similarly associated with both OIS (8.0 3.3) and NOIS (7.5 2.8)(P>.05). IS was more associated with poor outcome at dis-charge (52.2%) than NOIS (18.2%)(P<.05). Onclusions : Ischemic stroke after octogenarian age is characterized by different etiopathogenesis and poor short-term outcome compared to IS under that age. OIS is more frequently caused by cardiogenic embolism or combined underlying etiology, however, the relationship between differences in etiopatho-genesis and poor short-term outcome remains to be clarified. J Kor Neurol Ass 17(5):609~614, 1999 Key Words : Octogenarian, Ischemic stroke, Subclassfication