J Korean Neurol Assoc > Volume 16(6); 1998 > Article
Journal of the Korean Neurological Association 1998;16(6): 882-886.
전격성 횡문근융해를 보인 유방암환자에서 발생한 피부근염 1예
김정환, 정근호, 한동균, 정원희, 조필자*, 선우일남, 김승민**
국립의료원 신경과*, 연세대학교 의과대학 신경과학교실**
A Case of Fulminant Rhabdomyolysis and Dermatomyositis in a Patient of Breast Cancer
Jung Whoan Kim, M.D., Keun Ho Chung, M.D.,Dong Gyun Han, M.D., Won Hee Chung, M.D., Phil Za Choi, M.D*., Il Nam Sunwoo, M.D., Seung Min Kim, M.D.**
Department of Neurology, National Medical Center*, Department of Neurology, Yonsei University College of Medicine**
Abstract
A 58-year-old woman was admitted because of rapid growing left breast mass and slowly progressive generalized weakness. She was performed modified radical mastectomy due to infiltrating ductal carcinoma and received following chemotherapy with bromocriptine, 5-FU, MTX, Cyclophosphamide. On 45th hospital day, severe proximal muscle weakness and acute renal failure were developed abruptly, and performed hemodialysis. There is some improvement with steroid therapy, but she was expired 2 month later due to sepsis. We discribe the clinical and pathologic feature of a patient with dermatomyositis associated with breast cancer presenting as a sudden, rapid worsening condition leading to widespread muscle destruction and death. Key ward : Rhabdomyolysis, Dermatomyositis, Breast carcinoma
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