Two Cases of Holmes-Adie Syndrome

J Korean Neurol Assoc > Volume 16(4); 1998 > Article

Journal of the Korean Neurological Association 1998;16(4): 582-584.

Holmes-Adie증후군 2례

이상원, 윤성민·김광수·유경무

고신대학교 의학부 신경과학교실

Two Cases of Holmes-Adie Syndrome

Sang Won Yi, M.D., Sung Min Yoon, M.D., Kwang Soo Kim, M.D., Kyung Mu Yoo, M.D.

Department of Neurology, Kosin Medical College

Abstract

Background : Adie's tonic pupil consists of mydriasis, accommodation defect, decreased light reflex, and tonic near reflex. When tonic pupil is combined with hypo- or areflexia, it is called Holmes-Adie syndrome. Case : Fifty-two-year-old and 37-year-old female patients showed unilateral dilated irregular pupil, decreased light reflex, and decreased or absent DTR. When 0.125% pilocarpine was dropped on the dilated pupil, the pupil was constricted after pilocarpine application. Somatosensory evoked potentials were within normal ranges, and H-reflex responses were absent or delayed. Key Words : Holmes-Adie syndrome, Pilocarpine, H-reflex