J Korean Neurol Assoc > Volume 14(4); 1996 > Article
Journal of the Korean Neurological Association 1996;14(4): 930-939.
후두부 발작성 간질파와 동반된 양성 소아기 간질의 임상적 연구
유영수, 이상도 김지언 임정근 박영춘
계명대학교 의과대학 신경과학교실
Clinical Study of Benign Childhood Epilepsy with Occipital Paroxysms(BCEOP)
Young-Soo Yoo, M.D., Sang-Doe Yi, M.D., Ji-Eun Kim, M.D., Jeong-Geun Lim, M.D., , Young Choon Park, M.D.,
Department of Neurology, Keimyung University School of Medicine
Abstract
Background & Objectives : Although benign childhood epilepsy with controtemporal spikes (BCECT) has been well characterized and extensively studied, the clinical findings and prognosis of benign childhood epilepsy with occipital paroxysms (BCEOP) have been less well understood. The purpose of this study was to evaluate clinical manifestations, responses to antiepileptic drugs, and longterm. Prognosis of BCEOP. Methods and Subjects : We studied 10 BCEOP patients seen between 1985 and 1995 and followed up from 2 to 14 years(7.2±2.9). Results : In 10 patients, there were 7 females and 3 males. The age of onset ranges from 4 to 9 year-old(6.4±1.5). In the cases whose age of onset was below 6 year-old, the main clinical manifestations were tonic deviation of eye bal1, ictal vomiting and frequent development of status epilepticus in the sleep. In the cases whose age of onset was above 7 year-old, the main clinical manifestations were visual symptoms (blurring or blindness) associated with ictal vomiting/headache and complex visual hallucination evolved to automatism. The typical EEG findings were occipital paroxysms, characterized by repetitive high amplitude spike or sharp and slow wave complexes in the occipital area, mainly when the eyes were closed. Except one patient, the seizures responded well to anticonvulsant therapy and did not occur after the age of 11. Conclusion : Although the number of cases was small and the follow-up period was not long enough, our data indicated that BCEOP had a good prognosis and showed diverse clinical manifestations, which might be dependent on the age of onset.


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