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Journal of the Korean Neurological Association 1995;13(2): 390-396.
범하수체기능저하증과 동반된 근강직증후군 1례
김광수, 유경무, 김중규
고신대학교 신경과. 일반외과
A Case of Stiff-Man Syndrome Associated with Panhypopituitarism
Kwng Soo Kim, M.D., Kyung Mu Yoo, M.D., Joong Kyu Kim, M.D
Department of Neurology, General Surgery Kosin Medeical College
Abstract
Stiff-man syndrome is a rare disorder characterized by intermittent spasms and stiffness of the axial and limb muscles, associated with an electromyographic pattern of continuous motor unit activity in affected muscles. The cause of this disorder is unknown, but it has been associated with autoimmune disease and with endocrine disorder. We present a 49 year old female patient with clinical and electrophysiologic features of stiff-man syndrome and postoperative panhypopituitarism, whose muscle stiffness and spasm resolved with diazepam, clonazepam and prednisolonereplacement therapy.