| Home | E-Submission | Sitemap | Contact Us |  
top_img
Journal of the Korean Neurological Association 1995;13(2): 263-270.
당뇨병성 자율신경장애의 선별검사
강성수, 이규용, 권오영, 김희태, 김승현, 김주한, 안유헌, 김명호
한양대학교 신경과. 내과
Rapid screening of autonomic dysfunction in asymptomatic ?diabetics
S.S.Kang M.D., K.Y.Lee, M.D., O.Y.Kwon, M.D., H.T.Kin, M.D., S.H.Kim, M.D., J.H.Kim, M.D., Y.H.Ahn, M.D., M.H.Kim, M.D.
Department of Neurology, Internal Medicine, College of Medicine, Hanyang University
Abstract
To determine the rate of subcilnical autonomic abnormalities in asymptomatic diabetic patients, non-invasive tests using cardiovascular reflexes were performed. Sixty diabetics without any clinical autonomic symptoms and/or signs, and agematched thirty healthy persons were selected as a patients group and normal control group, respectively. By using the computerized cardioanalyser(Autocardiner FCP-2201U), the results including R-R variation to deep breathing, Valsalva ratio, positional changes of heart rate and blood pressure were compared between two groups. Among the sixty diabetics, 44 subjects(73.3%) showed abnormal findings in at least one of autonomic function test. The sensitivity detecting autonomic abnormalities of the R-R variation to deep breathing, Valsalva ratio, positional changes of heart rate was 97.8%, 59%, and 31.8%, respectively. And the positional changes of blood pressure was not remarkable in all subjects. The R-R variation to deep breathing and Valsalva ratio significantly decreased in patient group(p<0.05). But the positional changes of heart rate(30:15 ratio) was not significant between two group (p>O. 05). It is consequently suggested that high percentage of asymptomatic diabetic patients show a subclinical autonomic abnormalities. In addition, the R-R variation to deep breathing and Valsalva ratio using cardioanalyser could be a good screening diagnostic test of diabetic autonomic neuropathy.