| 당뇨병성 자율신경장애의 선별검사 |
| 강성수, 이규용, 권오영, 김희태, 김승현, 김주한, 안유헌, 김명호 |
| 한양대학교 신경과. 내과 |
| Rapid screening of autonomic dysfunction in asymptomatic ?diabetics
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| S.S.Kang M.D., K.Y.Lee, M.D., O.Y.Kwon, M.D., H.T.Kin, M.D., S.H.Kim, M.D., J.H.Kim, M.D., Y.H.Ahn, M.D., M.H.Kim, M.D. |
| Department of Neurology, Internal Medicine, College of Medicine, Hanyang University |
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| Abstract |
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To determine the rate of subcilnical autonomic abnormalities in asymptomatic diabetic patients, non-invasive tests using cardiovascular reflexes were performed. Sixty diabetics without any clinical autonomic symptoms and/or signs, and agematched thirty healthy persons were selected as a patients group and normal control group, respectively.
By using the computerized cardioanalyser(Autocardiner FCP-2201U), the results including
R-R variation to deep breathing, Valsalva ratio, positional changes of heart rate and
blood pressure were compared between two groups.
Among the sixty diabetics, 44 subjects(73.3%) showed abnormal findings in at least one
of autonomic function test. The sensitivity detecting autonomic abnormalities of the
R-R variation to deep breathing, Valsalva ratio, positional changes of heart rate was
97.8%, 59%, and 31.8%, respectively. And the positional changes of blood pressure was
not remarkable in all subjects. The R-R variation to deep breathing and Valsalva ratio
significantly decreased in patient group(p<0.05). But the positional changes of heart
rate(30:15 ratio) was not significant between two group (p>O. 05).
It is consequently suggested that high percentage of asymptomatic diabetic patients
show a subclinical autonomic abnormalities. In addition, the R-R variation to deep
breathing and Valsalva ratio using cardioanalyser could be a good screening diagnostic
test of diabetic autonomic neuropathy. |
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