A Case of Primary Malignant Leptomeningeal Melanomatosis

J Korean Neurol Assoc > Volume 9(3); 1991 > Article

Journal of the Korean Neurological Association 1991;9(3): 357-361.

연수막에 발생한 원발성 악성흑색종증 1례

이영기, 변영주,박충서,최원희

영남대학교 신경과, 병리학.

A Case of Primary Malignant Leptomeningeal Melanomatosis

Yeung Ki Lee, M.D., Yeung Ju Byun, M.D. & Choong Seo Park, M.D. Won Hee Choi, M.D.*

Dep. Of Neurology & Anatomic Pathology *, Yeungnam University

Abstract

Primary malignant melaomatosis of leptomeninges is uncommon, not reported in the Korea to this time. Primary melanomatosis of leptomeninges are not associated with any specific clinical or radiological symptoms. The diagnosis was made by ultrastructural demonstration of malignant melanoma cells from CSF. The patient is 23 years male, who has had meningeal irritating symptoms such as intermittent headache. Nausea, vomiting and disturbed consciousness. Brain CT and MRI showed no mass lesion but cytology of cerebrospinal fluid revealed malignant melanoma cells. There was no evidence of extracerebral melanoma.