BAEP Studies in Non-insulin Dependant Diabetic Subjects

J Korean Neurol Assoc > Volume 5(2); 1987 > Article

Journal of the Korean Neurological Association 1987;5(2): 204-212.

비인슐린 의존성 당뇨병 환자에서의 뇌간청각 유발전위 연구

한설희, 김재문, 이광우, 이상복, 명호진

서울대학교 신경과.

BAEP Studies in Non-insulin Dependant Diabetic Subjects

Seol-Heui Han, M.D., Jae-Moon Kim, M.D., Kwang-Woo Lee, M.D., Sang-Bok Lee, M.D., Ho-Jin Myung, M.D.

Department of Neurology, College of Medicine, Seoul National University

Abstract

Brainstem auditory evoked potentials (BAEPs) were recorded in 30 normoacoustic diabetic subjects, aged between 41 and 67 (55.37+7.75 yr). The result were compared with those obtained from 20 agemached, normoacoustic control subjects. The BAEPs were abnormal in 46.7% of diabetic subjects, I.e., the interpeak latencies (IPLs) were significantly increased and the amplitudes were somewhat reduced. BAEP abnormalities were not related to glucose balance, duration of disease, presence of the diabetic retinopathy or somatic neuropathy. In conclusion, diabetic neuropathy is characterized not only by somatic and autonomic nervous system involvement but also by central nervous system (CNS) involvement. Measurement of BAEPs would be one of the useful, noninvasive, simple and reproducible procedures to detect CNS lesion, even in the subclinical stages of Diabetes Mellitus.